ELISA vs Nucleic Acid testing
ELISA kits inaccurate, NAT needed, say blood bank officials – Indian Express 1 Sep 2010
20 children get HIV, Hepatitis due to infected transfusion – THE HINDU 12 July 2010
There has been a spurt of reports in the media in recent times suggesting Nucleic Acid Testing (NAT) would have prevented these incidences of transfusion associated infections and ELISA testing in ineffective.
I agree with all that the onus of providing safe blood rests on the blood centres. What I do not agree is the rumour spread by the media about ELISA and some “professionals” working in blood transfusion services falling prey to the well-orchestrated campaign of the manufactures and distributors of NAT.
The reasons for these reported incidents could be many fold – inappropriate selection of blood donors (most critical link in blood safety), use of ELISA kits of substandard quality, inappropriate storage and inadequate training in performing the tests. All these need to be looked into and appropriate corrective / preventive measures instituted.
ELISA is a Time-tested Technology and in fact in recent times the fourth generation tests have been released for use in blood centres.These tests for HIV, Hepatitis B and Hepatitis C are as clinically sensitive as NAT and can easily be automated and performed on the machines already available in the blood centres of India. Only ignorant "professionals" and those with "other" intentions can talk of NAT being made mandatory or ELISA is bad technology, at the cost of taxpayer's money.
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